2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N4106
    Dihydroartemisinic acid
    		Inhibitor 99.58%
    Dihydroartemisinic acid (Dihydroqinghao acid) is a biosynthetic precursor to the antimalarial agent Artemisinin (HY-B0094).
    Dihydroartemisinic acid
  • HY-U00295
    Melarsonyl
    		Inhibitor
    Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl
  • HY-153021
    NMT-IN-1
    		Inhibitor ≥98.0%
    NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis.
    NMT-IN-1
  • HY-18719ES
    Endoxifen-d5
    		Inhibitor
    Endoxifen-d5 is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study.
    Endoxifen-d<sub>5</sub>
  • HY-135648
    PfDHODH-IN-1
    		Inhibitor 99.12%
    PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity.
    PfDHODH-IN-1
  • HY-113715
    Niclofolan
    		Inhibitor 99.55%
    Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection.
    Niclofolan
  • HY-B1244S
    Dimetridazole-d3
    		Inhibitor 99.87%
    Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.
    Dimetridazole-d<sub>3</sub>
  • HY-121002
    Alstonine
    		Inhibitor
    Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties.
    Alstonine
  • HY-B0744C
    L-Eflornithine
    L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1.
    L-Eflornithine
  • HY-117025
    Manzamine A
    		Inhibitor 98.2%
    Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1.
    Manzamine A
  • HY-119819
    Psicofuranine
    		Inhibitor 98.0%
    Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth.
    Psicofuranine
  • HY-118224
    BPH-715
    		Inhibitor 99.62%
    BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells.
    BPH-715
  • HY-W019829
    Polyphyllin C
    		Inhibitor
    Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities.
    Polyphyllin C
  • HY-P5285
    Lunasin
    		Inhibitor
    Lunasin is a bioactive peptide with antioxidant, anti-inflammatory, anticancer and anti-aging properties. Lunasin can be isolated from soybean. Lunasin also has an epigenetic mechanism of action associated with histone acetylation. Lunasin can be internalized into cells and inhibit Oncosphere formation in cancer cells.
    Lunasin
  • HY-B2186
    Piperazine adipate
    		Inhibitor 98.0%
    Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
    Piperazine adipate
  • HY-B1934S1
    Methyl stearate-d35
    		Inhibitor
    Methyl stearate-d35 is the deuterium labeled Methyl stearate (HY-B1934) . Methyl stearate, isolated from Rheum palmatum L. is a compopent of of soybean and rapeseed biodiesels.
    Methyl stearate-d<sub>35</sub>
  • HY-107771
    Fluensulfone
    		Inhibitor 99.52%
    Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.
    Fluensulfone
  • HY-N8471
    Niazinin
    		Inhibitor 99.94%
    Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity.
    Niazinin
  • HY-78131S2
    Ibuprofen-d4
    		Inhibitor 99.28%
    Ibuprofen-d4 is a deuterium labeled Ibuprofen (HY-78131). Ibuprofen is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers.
    Ibuprofen-d<sub>4</sub>
  • HY-115249
    Metronidazole acetic acid
    		Inhibitor 99.88%
    Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa.
    Metronidazole acetic acid
Parasite Isoform Comparison

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